Leader in Medicine

Wolf H. Stapelfeldt


Dr. Wolf H. Stapelfeldt, Professor and Department Chairman at St. Louis University, has been recognized as a “Leader in Medicine” among “America’s Best Doctors” for 2017. Dr. Stapelfeldt was selected based on his knowledge and expertise in Anesthesiology and Organ Transplantation.

In his current capacity as Tenured Professor and Department Chairman at St. Louis University since 2014, his day-to-day responsibilities include the oversight of the Anesthesia Department, researching and improving outcomes while providing anesthesia services with an emphasis on minimizing harmful intraoperative hypotensive exposures. Dr. Stapelfeldt has authored over eighty-five academic research contributions with his research focused on liver transplantation and on creating predictive models, as well as developing electronic systems to allow physicians make better and more informed clinical decisions in real time at the various points of perioperative patient care.

He serves as one of the Founders and as the original Chief Medical Officer of Talis Clinical, LLC, a Cleveland Clinic spinoff information management company. Talis Clinical has created software that distills and analyzes patient information in real time to guide physicians in the high stress high acuity care environments of the ORs, PACUs and ICUs.

Following graduation with his medical degree summa cum laude from the University of Ulm School of Medicine in Germany in 1983, Dr. Stapelfeldt pursued a post-graduate residency in internal medicine at Klinikum Rechts der Isar in Munich, and a fellowship in physiology and a residency in anesthesiology at the Mayo Clinic in Rochester, Minnesota.

Prior to his role as the Professor and Department Chairman at St. Louis University, Dr. Stapelfeldt has held a series of leadership positions and appointments including those of  Chairman of the Department of General Anesthesiology at the Cleveland Clinic, Professor and Chairman of the Department of Anesthesiology at the University of Florida College of Medicine, Director of Liver Transplant Anesthesiology and Director of Research for the Anesthesia Service at the VA Medical Center in Pittsburgh, and Assistant Professor of Anesthesiology at the University of Pittsburgh Medical Center (UPMC). Additionally, he served as the Assistant Professor of Anesthesiology and Physiology at Mayo Clinic in Rochester, Minnesota.

As a testament to his success, Dr. Stapelfeldt’s contributions over the course of his career have been recognized with a ‘Top Ten in Medicine’ Innovations Award at the Cleveland Clinic, a U.S. Department of Veterans Affairs Merit Review award, a Young Investigator Award from the Foundation for Anesthesia Education and Research (FAER) and Roche Laboratories as well as Resident of the Year and Edward C. Kendall Awards from the Mayo Clinic.

Garnering over three decades of medical expertise, Dr. Stapelfeldt owns several patents and trademarks related to Clinical Decision Support technologies  and is the creator of the SLUScore™ perioperative risk scoring concept. Additionally, he has provided seminal assistance in the establishment of liver transplant anesthesia programs at the Mayo Clinics in Jacksonville, Florida, and in Phoenix/ Scottsdale, Arizona, as well as at the Children’s’ Hospital in San José, Costa Rica.

Looking back, Dr. Stapelfeldt attributes his success to being a part of great healthcare organizations and working in wonderful departments. His desire to pursue a career in Anesthesiology developed from his love for real time Physiology and Pharmacology.

To further his professional development, Dr. Stapelfeldt maintains memberships with the American Society of Anesthesiologists (ASA), the International Anesthesia Research Society (IARS), and the Healthcare Information and Management Systems Society (HIMSS).

As a certified single-engine pilot, Dr. Stapelfeldt enjoys flying sports planes in his free time. Other activities include his active engagement in animal rescue.

Considering the future, Dr. Stapelfeldt hopes and strives for the widespread realization of a substantial reduction in the significant postoperative morbidity and mortality that commonly ensues in the days, weeks and months following surgery and anesthesia.

St. Louis University

Professor and Department Chairman at St. Louis University

  • Founded in 1818, Saint Louis University is one of the nation’s oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.
  • From its earliest days, Saint Louis University has been guided by the Jesuit idea of magis (“more”) — achieving more, doing more, being more. A quest for excellence. A need to change lives and to make the world a better place. And so, what started in a house  near the banks of the Mississippi River has grown into a vibrant, world-­class institution. One ready for its third century of leadership.
  • SLU is a major catalyst for urban renewal in the heart of a vibrant city. In fact, they contribute more than $715 million in annual economic impact to the region and support more than 6,800 jobs in the St. Louis metro area.


  • The SLUScore: A Novel Method for Detecting Hazardous Hypotension in Adult Patients Undergoing Noncardiac Surgical Procedures.2017. PubMed
  • A Randomized Trial of a Supplemental Alarm for Critically Low Systolic Blood Pressure. 2015. PubMed
  • Duration of hypotension (still) matters.2015. PubMed
  • Outcomes after liver transplant in patients aged 70 years or older compared with those younger than 60 years. 2009. PubMed
  • Motor and somatosensory evoked potentials: their role in predicting spinal cord ischemia in patients undergoing thoracoabdominal aortic aneurysm repair with regional lumbar epidural cooling. 2008. PubMed
  • Dynamic left ventricular outflow tract obstruction during liver transplantation: the role of transesophageal echocardiography. 2007. PubMed